Working together. Saving lives.

History of UNOS

UNOS was founded to help the community of donation and transplant professionals make the best possible use of organs to save lives. It has played a vital role in the evolution of transplant therapy in the United States for more than 30 years.

Learn about transplant history

From the mid-1950s through the early 1970s, individual transplant hospitals and organ procurement organizations managed all aspects of organ recovery and transplantation. If an organ couldn’t be used at hospitals local to the donor, there was no system to find matching candidates elsewhere. Many organs couldn’t be used simply because transplant teams couldn’t locate a compatible recipient in time.

How we began

The South-Eastern Organ Procurement Foundation (SEOPF), an association of donation and transplant professionals, sought to increase the efficiency of organ placement. SEOPF established a computerized database in 1977 for each of its member institutions to list candidates and help them find matches for organs they couldn’t use locally. That database was called the United Network for Organ Sharing. In 1982, SEOPF launched a call center in Richmond, Virginia, to provide personal assistance with organ placement. That service, in continual operation ever since, is now the UNOS Organ Center.

By the early 1980s, more transplant hospitals were opening and many more candidates were being accepted for transplantation. The Congress of the United States passed the National Organ Transplant Act in 1984. The law called for a national network to coordinate the allocation of organs and collect clinical data about organ donors, transplant candidates and transplant recipients.

UNOS at work

UNOS was incorporated as an independent, non-profit organization in March 1984. UNOS was awarded the initial contract in 1986 to develop the requirements for the operation of the OPTN and has served as the OPTN ever since.

UNOS has grown from a handful of staff members in rented office space to an organization employing more than 350 staff members at its headquarters in downtown Richmond, Virginia. Its responsibilities have also increased and changed as the field of transplantation has matured. What has not changed is the commitment of UNOS staff to save and improve lives through uniting and supporting the efforts of the transplant community.



Working by phone, fax and manual logs, UNOS organ placement specialists work to save lives. UNOS was initially the name of a computer system used by some transplant doctors in the southeast to share organs. Guided by UNOS founding executive director, Gene Pierce, UNOS becomes the national network of transplant professionals working together to save lives. On March 21, 1984, UNOS is incorporated as the non-profit entity for this purpose.



UNOS’ first “IT department” is essentially one person, Jim Strawn. Our “state of the art” computer system is a VAX-11/750 server with a 32-bit microprocessor — less capacity than what you can find in home appliances today.

As the science of transplantation advances, so does the technology needed to match donors with the ever-growing number of transplant candidates on the waiting list. UNOS’ IT staff grows to more than 130 in 2014. These professionals ensure that the national electronic matching system runs accurately and securely, 24 hours a day, 365 days a year.



UNOS researcher, Bill Vaughan, reviews one of the earliest life-saving transplant match runs generated.

Prior to 1986, transplant centers were not required by law to share organs.

The federal contract establishes UNOS as the national Organ Procurement and Transplantation Network (OPTN), and makes UNOS responsible for allocation policy, organ placement, data collection and analysis, and public and professional education regarding organ transplantation.



UNOS receives a three-year contract to continue serving as the OPTN. Within the next three decades, UNOS coordinates more than 460,000 transplants from deceased organ donors.

UNOS also establishes the Scientific Registry of Transplant Recipients (SRTR) for analyzing key data on organ donation and transplantation and post-transplant survival. This information is used to develop allocation policies that are fair and save as many lives as possible. UNOS operated the SRTR until 2000.

1988, Bill Lawrence


Bill Lawrence received a liver transplant in 1988. He joined UNOS as director of patient affairs and supported the Patient Affairs Committee.

UNOS believes people who are directly affected by allocation policies should have a say in their development. UNOS creates the Patient Affairs Committee to directly involve patients in the policy-making process.

In 1988, UNOS collected data on all 12,623 transplants performed nationwide. Today, more than double that number occur each year. The data UNOS collects on each and every transplant is used to analyze the effectiveness of transplant policies and make ongoing improvements.


UNOS establishes 11 regions of the country to help determine the allocation sequence of abdominal organs. Each region has a representative serving on the UNOS Board of Directors and on most committees, to ensure thorough consideration of how transplant policy may affect people and institutions in all areas of the country.



A 64-year-old woman shows her signed organ donor card in late 1989. In recent times, a liver from a 93-year-old man was successfully transplanted.

A study done by UNOS’ Ad Hoc Donations Committee finds that organs from older deceased donors can perform as well as organs from younger donors. UNOS’ research concludes that these types of organs can help reduce the number of patients dying for lack of a suitable organ.



Kidney recipient George Franklin started the Quarter Century Club for organ recipients who are 25 or more years out from transplant. George’s kidney is doing great after 38 years!

UNOS releases the first comprehensive, national study of one-year transplant recipient survival rates for patients transplanted in 1988. In the nearly 25 years since then, survival rates improve substantially for most types of organ transplants.


UNOS helps establish the Coalition on Donation (now known as Donate Life America) to promote organ and tissue donation.

Donate Life America is a separate nonprofit organization with affiliates nationwide – and an easily recognizable logo promoting the life-saving power of donation. (For more information, visit



“Rescue 911” airs UNOS’ 24-hour toll-free hotline.

“Rescue 911,” a popular television show, airs UNOS’ 24-hour toll-free hotline following a broadcast devoted to organ donation. The volume of calls from people interested in signing a donor card so overwhelms UNOS’ telephone capability that new programming has to be incorporated into our voice mail system to prevent it from shutting down. Today, registering as an organ, eye or tissue donor can easily be done online at



From the earliest days at UNOS, we welcomed visitors from other countries who wanted to learn more about the U.S. transplant system.

UNOS is the model for transplant systems around the world. We host visitors from such far off countries as Japan and Korea to study how our system works.



UNOS’ public website is among the first to provide comprehensive medical information.

UNOS launches the first version of its website. It’s among the first public websites to provide comprehensive information, including data, news and resources, for any form of medical treatment.

Nineteen years since its founding, UNOS’ family of websites has an undisputed source of transplant information for patients and their families.



Every statistical report from UNOS is produced by dedicated researchers like Erick Edwards, who know that patients’ lives depend on their work. Erick joined UNOS is 1990.

Statistical modeling is used for the first time in policy development, to anticipate the likely effects of a policy before it is approved and implemented. But UNOS researchers are keenly aware that statistics are not merely numbers; they represent patients who depend on UNOS to save and improve their lives.



The Smithsonian Institution honors UNOS’ innovative use of technology: our computer system for matching donors with transplant candidates. Information about the design of the match system is incorporated into the Smithsonian’s permanent research collection on information technology.


UNOS publishes What Every Patient Needs to Know, a comprehensive booklet for potential transplant candidates and their loved ones. Updated through several editions, it has helped more than 250,000 people gain a better understanding of the transplant process.



UNOS launches UNet, a fundamental redesign of our technology for organ matching and data management. UNet is a highly secure, Internet-based application, constantly linking with professionals at more than 300 transplant hospitals and organ procurement organizations nationwide.


The new focus on policy compliance in 2000 leads UNOS to create a Department of Evaluation and Quality, which includes site surveyors like Margaret Kearns.


UNOS bestows a special Life-Giving Service award on the Tennessee Air National Guard (Lt. Col. Ed Joyce, flight navigator) and Tennessee Donor Services (Jill Grandes) for getting a liver from Tennessee to Texas for an infant during the flight ban after the tragedies of September 11.

Despite the disruption of air travel caused by the tragic events of September 11, UNOS continues to provide life-saving service. In one case, a National Guard flight crew is engaged to transport a liver from Tennessee to Texas for an infant in critical condition. No transplant candidates are known to have died that day because they did not receive an organ destined for them.


In partnership with sister organization, Donate Life America, UNOS creates a new logo.


UNOS establishes a new headquarters in downtown Richmond, featuring the National Donor Memorial. This 10,000-square-foot garden symbolizes the emotional experience of families during the donation process while honoring the lifesaving gift of organ and tissue donation.

UNOS welcomes visitors who have personal experience with organ donation or transplantation, as well as anyone who wants to learn more about the transformation made possible in so many lives through the act of donation.


A grateful lung recipient, Isa Stenzel Byrnes, starred in an award-winning documentary with her twin sister, who also received a lung transplant.

UNOS approves a ground-breaking change to lung allocation policy based more on medical urgency than on waiting time. The new policy gives priority to patients who are at the greatest risk of dying and have the highest probability of success. Since its implementation, pre-transplant deaths among lung candidates decrease by about 50 percent.


Every year UNOS enjoys receiving a special Valentine card from Mitchell Blakey and his family, celebrating Mitchell’s heart transplant in February 2007.

UNOS approves an improved heart allocation policy, updating the criteria used to identify urgent patients and give them greater allocation priority. In the years that follow, pre-transplant deaths among heart candidates decrease by about 25 percent.


Living donor policies protect living donors like John Mastro, who gave his liver anonymously. He was later able to meet his recipient, Jose Casteneda.

UNOS is given additional responsibility concerning living donation, when the federal government directs UNOS to develop policies for living donor transplants. This directive puts further emphasis on protecting living donors and strengthening trust in our national transplant system.


Non-directed kidney donor Matt Jones kicks off a paired kidney chain in July 2007 that ultimately results in 16 recipients when it ends in 2011. At Matt’s wedding in 2008, he dances with the woman who received his kidney, Barb Bunnell.

Congress passes legislation clarifying its support of paired organ donation. The legislation, which was initiated by UNOS in 2004, paves the way for UNOS to begin exploring a national kidney paired donation program.


Heart transplant recipients and siblings Zion and Zhania Coleman received transplants within a year of each other. Their mom says that needing the gift of life twice taught their family to cherish every moment.

UNOS modifies several organ allocation policies to reduce the risk of wait list deaths among pediatric patients. Following the enactment of these policies, pediatric wait list deaths decrease by more than 35 percent.


After her first liver transplant failed, Patti Dean’s husband Michael became her living liver donor. Her passion for telling her story and promoting donation led to a career at a local organ procurement organization.

UNOS’ Living Donor Committee develops guidance for transplant hospitals to use in creating medical evaluation protocols for living kidney donors and to medically evaluate potential living liver donors. The goal is to increase the level of patient safety throughout the nation.


The first transplant arranged through the OPTN KPD pilot program involved two pairs: one in St. Louis and the other in New Hampshire. Pictured are living kidney donor Rebecca Burkes with her recipient Ken Crowder and transplant surgeon Jason Wellen, M.D.

UNOS initiates the OPTN Kidney Paired Donation (KPD) pilot program. In December, the first two KPD transplants are performed. Since then, more than 85 people have been transplanted through the program. 15 percent were very highly sensitized, meaning that without a matching donor they’re likely to wait years longer than most people do for a deceased donor kidney.


James Carter receives the 2011 National Donor Memorial Award of Excellence for his extraordinary volunteer efforts in promoting organ donation for more than two decades.

UNOS’ National Donor Memorial Award of Excellence recognizes exceptional advocates for organ and tissue donation, especially “unsung heroes” who have not received recognition at a national level.

Because transplantation depends on the public’s trust and willingness to donate organs, the efforts of such individuals are vital to saving lives through transplantation.


Dylan Prescott lived with diabetes and failing kidney for four years. Thankfully, in 2013, his girlfriend, Jennifer, was able to give him a kidney.

UNOS’ Board of Directors creates greater consistency among hospitals that perform living donor transplants. Several new policies regarding the medical and psychosocial evaluation and informed consent processes for living kidney donors pass. Greater emphasis is being placed on helping potential living donors make informed decisions.


Highly sensitized kidney recipients like Melissa Bensouda, whose body would reject most kidneys, will benefit under the new system should they need another transplant.

After many years of research, analysis and gathering input from the transplant community, UNOS’ board adopts a major upgrade to national kidney policy. The policy may reduce transplant recipients’ future need for repeat transplants, thus allowing more transplants among candidates awaiting their first opportunity.


Double hand recipient Lindsay Ess, who is the patient representative on the new VCA committee, proudly shows her support of UNOS at our United for UNOS event.

UNOS enters a new frontier of transplantation – hand and face transplants – with the formation of a Vascularized Composite Allograft (VCA) Committee. The committee’s recommendations will guide the creation of national policies, including the matching of hand and face donors with patients who need them.


UNOS unveiled its new logo as part of a refreshed brand effort, which positions UNOS as the largest transplant network in the world.

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